20 Comments

Thank you for this format of different points of view regarding deeply involved subjects. We see so little of this kind of informed discussion and it can, at the very least, make one less apt to jump to a conclusion in situations where there are not clear paths to solutions. Especially when so well written it also helps to battle TLDR syndrome :-)

Expand full comment
author

Thank you! And I'm hoping these will be ongoing conversations... These are important, substantive topics and I'm hoping that we can elbow out space for real debate and substantive discussion.

Expand full comment
founding

Appreciate the thoughtful and informative write ups.

My fear/guess is that our “famously fractured and decentralized” healthcare system combined with our new found dysfunctional planning capabilities, will put us into a free-for-all system very soon after we run through the cohort that’s highly prioritized, easily identifiable, and readily physically accessible

Expand full comment

Most informative. Thank you to both you and Dr Robinson — and to all those working on this problem.

Expand full comment

I really love the Counter series and how much it opens up my own thinking (unlike falsely structured "debates," which don't ever seem to dig below the surface level). Thank you to Dr. Robinson for so clearly laying out the knowns/unknowns and reminding us how much it matters to gather date, to consider it carefully, and to use it well.

Expand full comment

I really appreciate this kind of science reporting/writing. Clearly outlining the complexities, challenges, and unknowns we are facing is exactly what's needed at the moment.

Expand full comment

It seems to me this discussion is more appropriate for a world where we can depend on logistical institutions to reliably follow the rules authorities set, and where people will reliably line up in the priority order authorities determine to take every available dose, than for the world we live in.

In the world we live in, vaccine doses are in danger of expiring because they can't get it together logistically to give them all out and/or not enough people are lining up for them. In the world we live in, the difference between the Israeli vaccination approach's speed and the US approach's speed seems very likely to matter far, far more than any prioritization rule tweaks we can make.

In that world, isn't the right course of advocacy and emphasis to shout from the rooftops and to every level of government official: treat this like a hurricane or an earthquake, deploy the National Guard, enlist paramedics and combat medics and veterinarians and so forth, get ALL the parallel vaccine administration capacity you can out there and get it running 24/7? Fretting over whether essential workers are going to get in line ahead of old people or whatever just seems penny wise and pound foolish compared to the imperative of treating this like a logistical emergency, which most of the West other than Israel is just not doing.

Expand full comment

Thank you Dr. Tufekci and Dr. Robinson for this thoughtful discussion. The various approaches in administering the vaccine reminds me of a morbid version of boarding airplanes, because no matter what factors go into the protocol, those with elite classification get to go first. I’d also done a 360 degree swing from pessimism -> optimism -> pessimism re: vaccines, as the seemingly feverish vaccine production from Pfizer and Moderna pre-authorization is unmatched by planning guidance and support from the Feds. We already see the debacle that ensues at the well-resourced Stanford Hospital, so it’ll be difficult for under resourced local health departments to lead vaccination drives for non-healthcare worker groups. The way I see this actually happening is provisioning by health insurance groups (e.g., Kaiser Permanente) to their members, with LHD targeting high-risk groups not covered by the employer-based health insurance companies, with help from community-based organizations.

Expand full comment

Thank you for this discussion. I was fully on board with age as the simplest and most direct determinant of vaccine eligibility, and probably still am, but I do understand these other factors. My main fear is that the introduction of any level of complexity will open up loopholes that ensure those who control the levels of power will be first in line to receive the vaccine. Age is a simple, immutable factor. Of course, then we get into the complexities brought up in the article regarding finding and classifying the elderly, ordering those within these strata, and engaging with vaccine hesitancies.

Expand full comment

Thank you for the very informative pieces. How worried are you right now about rate of vaccinations and actual distribution in states? CNN and others are running pieces on how 11.4 million have been distributed and only 2.1 million have been administered (data lag; other caveats withstanding) which both are less than 20 million number govt wanted. On top of figuring out how to prioritize vaccine, states and localities are are running their own logistics, and I am wondering how this will affect underserved and rural areas.

I am not a professional in any healthcare/public health fields, but I think Texas DSHS has said that after vaccinating the first tier of voluntary healthcare workers, do not wait to vaccinate 2nd tier (in TX it's 65+ or 16+ with comorbidities), and under circumstances vaccinate anyone available to not waste any extra dosages (guessing since vials go bad after a few hours once you start drawing). It sounds like TX is afraid of not vaccinating fast enough, but it is not as if locations are getting a list of people to vaccinate in multiples of 5 or 10 on any given day. Hoping that manufacturing problem will not be compounded by waste.

Expand full comment

Re: the pace. I’m very worried. In my article I emphasized that some state plans are not well-targeted to those at highest risk. But I’m also extremely worried about the pace and logistics. The Trump administration’s abdication of responsibility for coordinating a national vaccination that is clearly an interstate commerce issue is mind-boggling to me. Local health departments do not have the staff, IT infrastructure, database access or even freezer resources to execute this in the quickest manner possible. I don’t know of any other country that’s taking this kind of handoff approach. And waste is a real issue. Both US approved vaccines have to be kept frozen to prevent spoiling, the Pfizer-BioNTech especially. Ive already read one news account of a loss of hundreds of doses at a local facility. And I’m sure that’s happening in more places but not being reported. This is a logistically monstrous undertaking. Shipping a bunch of samples to states during a public health crisis where governments, hospitals, and local public health already at a breaking point and saying, “Ok, go vaccinate people. Good luck.” is not the best approach in terms of speed or optimal targeting. This is my belief based on the information available to me.

Expand full comment

I have participated in the Florida free-for-all on behalf of 85-year-old in-laws, who are not very internet-capable, and find themselves competing with 65-year olds for a limited supply of vaccine. After a couple of rounds of failures, we went into full-on attack mode - 12 computers and iPads with a total of 15 browsers across three locations launched at 6am to hunt two doses of vaccine. This finally, after 45 minutes of watching available vaccine numbers dwindle, produced success. I know we are far from being the only people who have resorted to this overkill. The authorities have created an arms-race almost perfectly designed to favor people with relatives with computers, high-speed internet and time available to engage in the battle - and to ensure that many of the neediest cases get vaccinated last, or simply give up.

Expand full comment
author

Yeah, that is TERRIBLE. I'm sorry. And exactly this, this is what's been happening.

Expand full comment

Looking at the racial disparity charts, I see something else. The tallest spikes for black and Hispanic death rates are in March / April 2020, when the epidemic in the US was basically confined to a few densely-populated cities with large black and Hispanic populations. Those areas hold a ledger proportion of the nation's black and Hispanic populations than of its white population. How do these charts look if you confine the denominator to the population of the regions affected by the pandemic.

Expand full comment

@zeynep would love your reaction/opinion to this art intervention (and how to make it better, more impactful). (Bitly link is a screenrecording of the experience - can also share the app experience too, if interested.) This is regarding Covid mortality numbers and how the public seems to be getting normalized/numb to the scope of the epidemic: https://bit.ly/CoronaBears_b3

Expand full comment

Fantastic piece, Whitney, I won't say a word against it. I was especially moved by the description of the NHS and it's extensive contact list, and am jealous that we do not have those here. But we don't. And so, the debate over who gets vaccinated first has become an intellectual parlor game, where we play the role of a room full of Chidi Adagonyes, agonizing over inherently equal and un-equal choices.

Stepping out of the parlor and into the news, two stories are simultaneously developing: that the wrong people are getting the first shots; and that the shots are not going out fast enough. Which makes sense, because the more you try to control and prioritize the rollout, the slower it will go.

Back when I used to study, I came across a set of six criteria for measuring quality of a given theory. I forget most of them, but empirical validity and parsimony have stuck with me. Prioritizing those >75 is simple and valid. Prioritizing all hospital staff is simple and valid. Prioritizing from multiple groups and multiple variables is valid, but not simple. If saving lives and SARS CoV-2 eradication are the goals, an orderly, efficient, trackable system to administer shots as quickly as they become available is what we need.

Considering that all their hospital workers are at the front of a very long line, Stanford might have been better off trying a different prioritizing algorithm: alphabetical order.

Expand full comment

I appreciate your comment and am also attracted to simple rubrics and rules. For instance, I saw some people on Twitter making fun of calling the Stanford weighted score an algorithm bc it wasn’t a complex machine learning tool. I actually think its (relative) simplicity is a strength. It would have taken much longer to identify the problem if it were some AI tool. (I also think the algorithm is more complicated than it looks. The 3 employment related variables are forced onto a 0-1 scale that obscures the distribution of underlying variation and makes it hard for me to intuit how much variation in these factors influenced variation among the scores. Also the CDPH part of the score, presumably based on the guidelines from the California public health authorities is a unclear to me). Complex bureaucracy can address inequities but they can also further them. I struggle with this in vaccine rollout.

A few thoughts: as I said, age seems simple and straight-forward and seems to be working efficiently in places like UK. But I think the decentralized health infrastructure in US and lack of federal preparation will make this strategy more complex than people think. Without a central roster to draw from, most places are using an advertisement and first-come, first-served (within state qualifications) system. I think the most high-risk people are most likely to fall through the cracks. A lot of my family live in southwestern Tennessee. TN appears to be adhering more closely to federal ACIP guidelines than FL and vaccinating some “essential workers” now too. A family member told me that there are drive-up locations where you show your employee ID and get a shot. In some ways, verifying a low-wage worker’s employment with a work ID is much easier than verifying someone’s age. I think that running these processes in parallel is worth trying. I honestly do not know which will vaccinate the most high-risk people fastest. (And overall efficacy in the strategy depends on how well the vaccine reduces transmission. If it does this, vaccinating younger people with lots of social contacts at work and home has important spillover effects.) Many workers under 65 are being exposed to the virus in unsafe conditions right now and continuing in January. And bringing exposure home to their families, who will then interact with older relatives who might not be able to get an appointment on an online portal that fills up within hours or stand online all day. So there’s a trade off there too. Anyway, there are answers to these questions. In five years, we will have studies that tell us which strategies saved more lives. Or maybe it’ll be less about exact prioritization than overall coordination, local competence, and funding.

Oh, one more thing! The Stanford algorithm’s inclusion of a CDPH variable inspired me to look at California’s vaccine allocation plan. Just phase 1a is like pages long. And at first I was dubious (because, like you, I don’t really think complexity all that great). But the length wasn’t from complex algorithms. It was from giving alternatives for lots of different scenarios. To me, It was saying, “Hey, local health departments! I know your situations and challenges are going to vary. We took the time to think through that and offer you suggestions for how to execute this in your own setting.” I actually think that’s the kind of complexity/nuance we need. A seemingly simple rule like Florida’s seems straight forward but doesn’t actually give local health departments tailored suggestions that they can apply quickly. So they are all each reinventing the wheel to put systems in place. I think this is a case in which simplicity (lack of planning for variable on-the-ground conditions) is a barrier to faster implementation.

Expand full comment

Wow. I am loving these Counter Point articles! Learning so much. I do believe prisons have a relatively low death rate (among inmates) very unlike nursing homes. But of course one has to consider the staff as well, and potential superspreading events. Dr Robinson's Venn diagram was brilliant!

I don't understand her comments on known unknown #6 - it seems like driver's licenses, etc all have information on ages, so that appears to me to be an easy gate to validate.

Finally, I like her very humble finish on unknown unknowns, reminds me of what Dr Osterholm constantly says about what he thinks is next. Again -- THANKS so much for these!

Expand full comment

Hello Paul. For information on high COVID-19 mortality rates in prisons, here’s an article from JAMA on deaths this spring: https://jamanetwork.com/journals/jama/fullarticle/2768249. For more up-to-date data, “The Marshall Project” is a good follow. And they have a good dashboard. As an epidemiologist, I consider the numbers of COVID deaths a lower bound because of limited testing and possible undercounts in many jurisdictions. https://www.propublica.org/article/inside-the-uss-largest-maximum-security-prison-covid-19-raged

And, if you’re more concerned about staff than inmates, it’s still a good argument for vaccinating inmates in addition to staff. From what I’ve read, managing prison and jail facilities was already an extremely demanding and sometimes traumatizing job. Now add onto that losing the ability to offer activities and socialization to the population as incentives had ways to cope and blow off steam. Now add onto that the management of huge infectious disease outbreaks. Now add onto that the moral injury from the suffering you witness even from people who don’t die. I think most prison staff want to do some good. They didn’t sign up to preside over these huge outbreaks. Also you might be interested in this.

Also have you heard about prison guards suing the federal prison bureau re: COVID-19?

https://www.washingtonpost.com/politics/union-sues-to-get-hazardous-duty-pay-for-federal-workers-exposed-to-the-coronavirus/2020/03/30/93b57f8e-72b3-11ea-a9bd-9f8b593300d0_story.html

https://www.washingtonpost.com/nation/2020/08/24/prisoners-guards-agree-about-federal-coronavirus-response-we-do-not-feel-safe/

Now number #6. There are many information systems in the US, but they are not connected. For instance, the best relatively updated roster of older Americans (although still incomplete) is probably Medicare. But that’s a federal program. Local health departments don’t have access to Medicare rolls. Now the federal government could have spect the past 6 months developing a data linkage that local governments could access. To my knowledge, they have not. You also mention drivers licenses. This is ok but not perfect: 1) many people don’t have drivers licenses with up to date info, especially older and poorer people. Also I don’t think most licenses include phone number info. In the UK, every person has a GP (assigned primary care doctor). And these folks are responsible for the care of all patients in their portfolio and have up to date contact info on them. So local GP

offices can have been calling everyone who is eligible in a tier and saying, It’s your turn. I think this is what would easiest for most Americans, a system where a trusted entity with whom you have an ongoing relationship calls or texts you and tells you that it’s your turn and where to come. State and local health departments are being creative to find other means but it’s not a proactive calling down the list like they are doing in UK (and I imagine Israel). We don’t have the existing data infrastructure for this like counties with centralized, universal health care systems. Admittedly, health care org and vaccination are not my areas of specialty. I welcome other information that you have to share.

And thank you for your kind words and thoughtful response to my article. I sincerely appreciate it.

Expand full comment

Thanks so much Dr Whitney! Appreciate the info and follow up links, I have lots to learn.

Expand full comment